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At a median follow-up of 55 months, tamoxifen reduced the risk of invasive breast cancer by 49% and noninvasive cancer by 50%, as well as a reduction in hip, radius, and spine fractures was observed, while, the risk of endometrial cancer and the incidence of thromboembolic events also increase accordingly

CentralGoogle Scholar Liu DS, Duong CP, Haupt S

Each patient failed previously to respond to at least three different immunmodulatory/antifibrotic drugs (Table 2)

The Mayo Score is used to assess the severity of ulcerative colitis 7,8 The Mayo Score consists of 4 factors: Physician Global Assessment Endoscopy findings Stool frequency Rectal bleeding severity The Mayo Score ranges from 0-12, with higher scores indicating more severe disease