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Autonomic nervous system dysfunction (ANSD) is a relevant contributor to some of the clinical features in RTT patients that leads to multiple impairments ranging from anxiety, GI dysfunction, breathing disturbances, peripheral vascular control alteration (19) to sleep issues (3), heart rate variability (HRV) (2022), and increased risk of sudden death (23, 24)

1 A randomised double-blind trial of 130 women showed that adding NAC to letrozole produced more mature follicles and a modest but statistically significant pregnancy rate improvement (p = 0.045) compared with letrozole plus placebo

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Adicionalmente, las mujeres embarazadas o en periodo de lactancia deben consultar a su mdico antes de tomar este suplemento