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Patients with severe heart failure or arrhythmias require monitoring because rapid shifts in free-fatty-acid metabolism can influence myocardial substrate utilization

After excluding 79 duplicates, 99 citations were screened, and 81 reports were removed

Similarly, analysis of 89 different mice strains revealed significant differences in microbial composition between the sexes, although the direction of the change in each strain varied, suggesting that the influence of sex on microbiota may depend on the animal overall genotype [54]

Thus, the demonstrated kinetics of generation and decay of the metabolites monitored followed the anticipated precursorproduct relationships, and were entirely consistent with the initial microbial conversion of l-carnitine to BB, followed by transformation of BB to TMA, reaction kinetics akin to the dynamics of l-carnitine catabolism observed with the human commensals P