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As a result, the blood may be unable to move in the intended direction and gets accumulated in the vein

and E.S.: data curation

Chronic high-dose vitamin B intake (generally in gram quantities daily over many months) has been linked to severe sensory neuropathy characterized by numbness, impaired proprioception, and paresthesia in a stocking-glove distribution

Preclinical studies have explored its potential effects on the gastrointestinal tract, muscles, ligaments, tendons, and nerves
