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Description
Iron (Fe 2+ ) generates large amounts of hydroxyl radicals through Fenton and iron-catalyzed Haber-Weiss reactions, catalyzing the generation of ROS, which in turn leads to the development of LP (MacKenzie et al., 2008

In addition, ATOX1 functions as a copper-sensitive transcription factor through interactions with Sp1 and metal regulatory transcription factor 1, thereby affecting genes involved in the oxidative stress response and neuronal plasticity (40,41)

Hold the vial up to good light and inspect before use

Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complex
