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Description
A recent study suggested that plasma levels of 5-MT, a compound related to serotonin metabolism, may be decreased in CFS patients, but this has been interpreted as a confounder caused by serotonin-selective reuptake inhibitor (SSRI) use in these patients ( The principal role of carnitine is to transport long-chain fatty acids into the mitochondria for energy production via beta-oxidation ( While carnitine supplementation could have benefits, some recent studies suggest that chronic oral L-carnitine administration may be associated with an increased risk for atherosclerosis via increased trimethylamine (TMA) and/or trimethylamine N-Oxide (TMAO) levels ( Mitochondrial dysfunction has been suggested to contribute to CFS ( The mechanisms that link carnitine intake, S-5-HT, and fatigue, in both CFS and hypothyroidism, are yet unknown

Despite its value as a noninvasive and longitudinal matrix, hair analysis has several inherent limitations that restrict its clinical and diagnostic applicability

The single biggest gap between expectation and reality is timing

Les FA hydrolyss sont des substrats pour l'oxydation des acides gras (FAO) et la synthse des VLDL ou lipoprotines de trs basse densit (Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice 2016)
