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In another study, chlorophyllin treatment has been reported to cause cell cycle arrest in HCT116 colon cancer cells through the increased expression of E2F1 and E2F4 transcription factors inhibiting the G1/S checkpoint step, which is an important cell cycle checkpoint (Chimploy et al
Cell Mol Biol Lett 27(1):37 Nabi-Afjadi M, Mohebi F, Zalpoor H, Aziziyan F, Akbari A, Moradi-Sardareh H et al (2023) A cellular and molecular biology-based update for ivermectin against COVID-19: is it effective or non-effective
