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In lung epithelial cells, glutathione S-transferase P (GSTP) can disrupt the tetramer of PKM2 through the S-glutathionylation of cysteine to induce dimer formation, disrupting the canonical glycolytic function of PKM2 [85]
Serum transferrin receptor levels in Friedreichs and other degenerative ataxias
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If a claim implies systemic benefits, treat it as a higher-uncertainty category and prioritise evidence quality over confidence
