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Description
Although choroidal melanin seems to be synthesized throughout life, melanin in the RPE is synthesized for a brief interval of fetal and perinatal life with little production thereafter [5658]

In summary, statins can promote the stability of atherosclerotic plaques by inhibiting the proliferation, migration, and apoptosis of SMCs and by affecting the collagen secreted by SMCs
(2018) 48:10141028.e6

As mentioned above, spotting can have normal causes such as ovulation, implantation, birth control, or perimenopause
