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In the ovaries, estrogen synthesis begins in theca cells with androgen production and is completed in granulosa cells via aromatase

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However, it is important to note that these mechanisms were identified in different experimental contexts, and their relevance to the observed effects of the complete SHFKO formulation in our ARD models requires validation through targeted mechanistic studies

Spectrinis major protein of the cytoskeleton & its two chains ( & ) are aligned in an antiparallel manner & chains are loosely interconnected forming a dimer, one dimer interact with another, forming a head to head tetramer