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This promoter is active in neural crest cells, and driving MYCN overexpression in these progenitor cells of NB causes the animals (Th- MYCN ) to develop tumors that closely resemble human NB ( in vitro

[DOI] [PMC free article] [PubMed] [Google Scholar] 14.Heymsfield SB, Greenberg AS, Fujioka K, et al

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Whilst B12 side effects in elderly individuals are generally mild and infrequent, understanding potential reactions helps optimise treatment safety