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doi: 10.3390/nu12010228, 76
130,153,154 mtDNA, mtRNA, ROS, and ATP in mitochondria are all able to act as agonists for inflammasomes
Importantly, recent reports have demonstrated that only prolonged (chronic) mitochondrial depolarization induces Parkin translocation or mitophagy in neurons (Figure 4.2) [180, 321]

Lycopene is involved in downregulating the serum levels of TNF- and IL-, hence reducing the inflammatory response at the choroid plexus and improving cognitive defects
