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Compared with ramucirumab (158), its single-drug effect was not obvious and clinical trials were not sufficient

Quick answer In the REDEFINE trials CagriSema is given once weekly by subcutaneous injection, with both components titrated in parallel from 0.25 mg + 0.25 mg up to a 2.4 mg + 2.4 mg weekly target

Mirikizumab for the treatment of moderate to severe ulcerative colitis

Cizza G, Skarulis M, Mignot E