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Relative bioavailability of generic and branded acetylcysteine effervescent tablets: A single-dose, open-label, randomized-sequence, two-period crossover study in fasting healthy chinese male volunteers

There is a preferential transport of GSSG from the cytosol to the endoplasmic reticulum to maintain an adequate environment for protein disulfide bond formation and protein folding (6971)

In fact, GSH depletion obtained by BSO, the irreversible inhibitor of GCL, is the most frequently used approach and it is associated with many chemotherapeutic agents [5357]

Sakura T, Hayakawa F, Sugiura I, Murayama T, Imai K, Usui N, Fujisawa S, Yamauchi T, Yujiri T, Kakihana K, Ito Y, Kanamori H, Ueda Y, Miyata Y, Kurokawa M, Asou N, Ohnishi K, Ohtake S, Kobayashi Y, Matsuo K, Kiyoi H, Miyazaki Y, Naoe T