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Description
S conformation and assembly state influence cytotoxicity such that shifting the levels of physiological -helical tetramers toward the more aggregation-prone monomers leads to S cytoplasmic inclusions, hyperphosphorylation, and neurotoxicity 42,43,51,52

127 YoshidaH.KisugiR

E., Musfeldt M., et al

doi: 10.1152/jappl.2001.90.6.2157
