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Excessive production and accumulation of ROS is a common denominator of toxicity, being involved in the development and progression of over 100 diseases

Human foreskin fibroblast (HFF) and endothelial cells (EC) pretreated with 2-phospho-ascorbate (ASC-2P) resisted CMV infection

Disease heterogeneity and complexity might be a hurdle that is simply too high to overcome by existing methodological approaches, and the way forward to interpretable trial results remains unclear

It helps preserve collagen through sirtuin activation, promotes autophagy in dermal fibroblasts, and enhances cellular responses to esthetic treatments