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There are many acyl-CoA synthetases, differing in acyl-specificity from acetyl-CoA to lignoceroyl-CoA, and in localization [29-32]

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PCT is the most common type of porphyria and is further categorized in two different subtypes: familial and sporadic.23 In the familial form, the enzyme defect is present in hepatocytes and other cells, such as erythrocytes
