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A network of epigenomic and transcriptional cooperation encompassing an epigenomic master regulator in cancer

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Due to the large impact of NCOA4 in cerebral ischemia-reperfusion injury, it has been shown that the autophagy-related 5 (ATG5)-ATG7-NCOA4 pathway also has an important role in ferroptosis (106)

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Additionally, it has been revealed that cannabidiol acts as a positive allosteric modulator at GABAA receptors, and observational trials have shown that CBD in the formulation of Epidiolex is indeed an effective analgesic in the treatment of LennoxGastaut disorder and Dravet syndrome [152,153]

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10.1001/archinte.153.21.2465 19 FukumotoK.IijimaM.ChakiS

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