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Discussion In the current study, we set out to evaluate pyroglutamic acidemia in both serum and urine as an increased oxidative stress predictor in critically ill patients with septic shock as well as its association with clinical outcomes, morbidity and mortality, and patient evolution in the ICU

Thyroid hyperplasia and nodular development can be induced by the use of rodent models and transgenic mice with mutations in genes such as Ras or TSH receptor mutations

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these hormones can exert specific physiological effects at very low concentrations [27]