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1 Introduction Sepsis-associated encephalopathy (SAE) represents a severe complication of sepsis, defined by diffuse brain dysfunction without direct central nervous system (CNS) infection (Young et al., 1990) and the overall mortality rate remains high at 25%50%, despite advances in critical care

Vitamin B12 injections can be particularly beneficial for several groups of individuals who may have difficulty obtaining adequate levels of this essential nutrient through diet alone

SECIS-binding protein 2 promotes cell survival by protecting against oxidative stress