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Tsc1 flox/+ , or HoxB7-Cre

Under various stress conditions, such as amino acid starvation, endoplasmic reticulum stress, hypoxia and virus infection, ATF4 (a member of the ATF/CREB transcription factor family) is mainly induced by mRNA translation (Pakos-Zebrucka et al., 2016)

These regulations exist to protect consumers from unregulated whitening cocktails that may contain harmful additives or incorrect concentrations

15(S)-HETE drives peritoneal macrophages toward an anti-tumor phenotype via the PPAR/C/EBP axis (268), while genipin inhibits CCR2 signaling through PPAR-mediated p65 degradation, reducing macrophage infiltration and preventing hepatocellular carcinoma recurrence (269)