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Studies also suggest that reduced copper levels in the hippocampus may impair synaptic plasticity and neuronal growth, leading to memory decline (77)

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About half of eyes with these retinal characteristics progress to PDR within 12 to 24 months, indicating a strong need for careful monitoring at this stage

Additionally, TRF administration led to a reduction in the number of CD4+ senescent T cells in the dermis and spleen, consistent with the reduced expression of senescence-associated genes in splenic CD4+ T cells