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El-Sayed et al

Current CED trials underway include liposomal irinotecan in high-grade gliomas (NCT02022644) and MDNA55 (an interleukin 4 receptor targeting toxin) in recurrent GBM (NCT02858895)

However, during the 12-month therapy, the patient developed a rash at the site of the cyanocobalamin injection [85]

Life Sci 32:19491955 Boussicault L, Herard AS, Calingasan N, Petit F, Malgorn C, Merienne N, Jan C, Gaillard MC, Lerchundi R, Barros LF, Escartin C, Delzescaux T, Mariani J, Hantraye P, Beal MF, Brouillet E, Vega C, Bonvento G (2014) Impaired brain energy metabolism in the BACHD mouse model of Huntingtons disease: critical role of astrocyte-neuron interactions