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As more insights on aging mechanisms have been uncovered, these hallmarks have been expanded upon to include disabled macroautophagy/compromised autophagy, chronic inflammation, and dysbiosis (Guo et al., 2022
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use of different expression systems can also effect both folding and active conformation of GGT, as uncoupling autoprocessing from enzymatic activity was successful for HpGGT and BpGGT but not for EcGGT
