glutathione ulcer stomach Metabolites Profiling and Bioassays Reveal Bassia indica Ethanol Extract Protective Effect against Ulcers Development via HMGB1/TLR-4/NF-κB Pathway Antioxidant, Anti-inflammatory, and Antiulcer Potential
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Lancet Glob Health 5(12):e1221e1234 Das S et al (2022) Innate immunity dysregulation in aging eye and therapeutic interventions

10.3389/fimmu.2024.1413485 129 UllahH.ArbabS.TianY.LiuC.-q.ChenY.QijieL.et al (2023)

Cerebral blood flow in patients with chronic heart failure before and after heart transplantation

Both in vivo and in vitro studies have demonstrated that high glucose levels upregulate Apelin (APLN) in SC, which subsequently downregulates cell junctionrelated genes such as connexin 43 (Cx43) and zonula occludens-1 (ZO-1), ultimately compromising the integrity of the BTB (50)
