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The only statistically significant drug-placebo difference observed was a decrease in heart rate for citalopram tablets of 1.7 bpm compared to no change in heart rate for placebo

- () - -500 mg - 3 -(L-Glutamine) -(L-Arginine) -(L-lysine)

Thus, it is interesting to note the case of monozygotic twins with trisomy 21 but with discordant phenotypes, as well as the case of subjects with DS phenotype but carrying a partial trisomy of a very restricted region (34 kb on distal 21q22) (452)