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The suggestion is that reduced GR activity and therefore less 'reduced glutathione' may be implicated in Irritable Bowel Syndrome - possibly because it has less defenses against free radicals, the cause of oxidative stress

Future studies should further dissect the specific roles of mitochondrial subcompartments (e.g., matrix and intermembrane space) in death signaling and explore strategies to achieve precise neuroprotection by modulating mitochondrial quality control networks (Fig

191 Very few studies have been performed to identify mammalian SDA-derived octadecanoids

2017;12(2):e0170900
