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Furthermore, the ratio of tryptophan to kynurenine, a key tryptophan metabolite, in urine negatively correlates with the disability score of patients with RRMS 167

However, under a tumorous environment, elevated expression of lysosome protease B can enzymolyze the two amide bonds of the link and cause cytotoxins to release in the complete active form

The major adaptive immune cells include T cells and B cells, and the function of adaptive immune cells is affected by lipid peroxidation ( Figure 2 )
