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This helps ensure a clean and responsible process
Typically, Fe 3+ is internalized and carried to endosomes by means of the transferrin receptor (Kawabata, 2019)

Physiologically, APP enters the non-amyloid pathway via alpha-secretase and gamma-secretase cleavage
In cytosol, inorganic sulfate is conjugated with adenosine monophosphate by adenosine triphosphate (ATP) sulfurylase to form adenosine 5-phosphosulfate (APS), which is subsequently phosphorylated under the action of APS kinase to form PAPS 10
