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Some types may contain small amounts of IGF-1, but its hard to know for sure because these supplements arent regulated

These effects may be more pronounced in patients with altered gastric anatomy Pancreatitis risk : Patients should be informed about symptoms of acute pancreatitis (severe abdominal pain, sometimes radiating to the back, with vomiting) and seek immediate medical attention if these occur Gallbladder disease : Increased risk of gallstones and gallbladder-related problems, particularly with substantial weight loss Dehydration and acute kidney injury : Reduced fluid intake combined with gastrointestinal side effects may increase risk of dehydration Nutritional concerns : The combination of reduced stomach capacity and appetite suppression may increase the risk of nutritional deficiencies, particularly protein, vitamin B12, iron, and calcium Hypoglycaemia risk : Especially in patients taking diabetes medications, careful monitoring and dose adjustment may be necessary Diabetic retinopathy : Patients with diabetes should have appropriate eye screening, as rapid improvement in glucose control may temporarily worsen retinopathy Medication absorption : GLP-1 receptor agonists may affect absorption of oral medications due to delayed gastric emptying Pregnancy and contraception : These medications are not recommended during pregnancy or breastfeeding

Additionally, because low NAD+ is linked to aging, its decline could contribute to the development of various age-related health concerns, including cardiovascular disease, metabolic disorders, the development of neurodegenerative diseases such as Alzheimers and Parkinsons, and cancer

However, 20.0% of 60s could be affected