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However, by 3 months, the cumulative effect of curcumin resulted in significant reductions in both Visual Analogue Scale pain at rest and during activity, when compared to the baseline and the placebo group

however, this process is negatively regulated by neutral endopeptidase 1 (ECE-1) (50)

Glucose Metabolism: Growth hormone is known to impair glucose tolerance and insulin sensitivity, sometimes precipitating diabetes or worsening glycemic control in diabetic patients
