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Description
Currently, a number of non-pharmacological therapies have gradually emerged in clinical practice for the treatment of NPP, such as transcranial direct current stimulation, mindfulness-based therapy, meditation therapy, and physical exercise, all of which have demonstrated favorable therapeutic outcomes (188, 189)

ERS can activate the expression of Ca 2+ release channels on inositol 1,4,5-trisphosphate receptors (IP3R), thereby mediating the release of ER-Ca 2+

IRE1, inositol requiring enzyme-1

TGF-1, Transforming growth factor-1
