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Moreover, pharmacological modulation of angiogenesis may serve new therapeutic purposes in the prevention of neurodegenerative diseases (Parkes et al
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doi:10.1016/0024-3205(94)00796-9 15
herein, we refer to OI and NIO as populations. The study was conducted in accordance with principles and requirements of the International Council for Harmonization Good Clinical Practice guidelines and the principles of the Declaration of Helsinki
