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This is consistent with a previous report that the core apoptotic pathway genes, including CED-9/BCL-1, CED-4/APAF-1 and cell-killing caspase ced-3 , are not required for axonal fusion 16

Ren A, Yan G, You B, Sun J

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A PPAR, NF-B and AMPK-dependent mechanism may be involved in the beneficial effects of curcumin in the diabetic db/db mice liver