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Among the two trans -epoxides ( R , R ) and ( S , S ), both plant and mammalian sEH have been shown to be enantioselective

doi: 10.1152/ajpcell.1995.269.6.C1371

Comparison to a synthetic standard supported the annotation of this peak as 4-bromonicotinic acid, although differences in fragment ion intensity between the synthetic and experimental MS/MS spectra meant that without access to the original sample, this structure remained a leading hypothesis rather than a definitive identification

Truthfully, while there is still some promising research around GHK when taken orally, most of these claims should be taken with a grain of salt