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In our previous experiments, the Atgstu19 mutants were characterized by lower vitality, higher H 2 O 2 levels, and less negative redox state in RAM compared to wild type plants under salt stress (Horvth et al

These canonical functions positioned DHODH primarily as a metabolic enzyme critical for nucleotide biosynthesis and cellular proliferation, before its more recent identification as a mitochondria-specific ferroptosis suppressor in select cancer contexts

Under metabolic homeostasis, astrocytes play a pivotal role in Gln synthesis via an astrocyte-specific enzyme, the GS 24

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