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They were a heterogenous group pursuing a variety of research topics revolving around the question of antibody diversity and formation (Lefkovits 2017)
Short-term IP exposure engaged cellular repair and stress response pathways, including DNA repair, E2F signaling, p53 pathways, oxidative phosphorylation, and NF-B-associated inflammation in females, features consistent with canonical responses to metabolic stress or tissue injury [4,24]
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This suggests that cobalt sensitivity might be a contributing factor to these skin reactions
