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Figure 3 Potential Therapeutic Measures of TMAO for AS Reduced Production of TMAO to Protect the Heart TMAO is an intestinal microbiota-dependent metabolite, which is accumulated in the body by ingestion of large amounts of substances rich in phosphatidylcholine

Primary carnitine deficiency (PCD) is an autosomal recessive disorder characterized by a lack of plasma membrane carnitine transport owing to a shortcoming in the OCTN2 carnitine transporter

This motif is present in the Na + -driven hOCTN1 and mOCTN3, but notably absent in OCTs and OATs, suggesting a possible OCTN-specific role of this motif

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