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In vivo and in vitro evidence for brain uptake of 4-phenylbutyrate by the monocarboxylate transporter 1 (MCT1)
Mol Biol Evol 17:12321239
In particular, cocaine treatment in mice has been shown to cause a bidirectional loss of activity-dependent synaptic plasticity in the nucleus accumbens core, which is a defect in both LTP and LTD of excitatory synaptic transmission [114]
