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Choice A: Decreased lung elasticity is the primary pathophysiologic mechanism of emphysema, which leads to hyperinflation and an obstructive pulmonary function pattern
Leucovorin, fluorouracil, and oxaliplatin plus bevacizumab versus S-1 and oxaliplatin plus bevacizumab in patients with metastatic colorectal cancer (SOFT): An open-label, non-inferiority, randomised phase 3 trial
The authors acknowledge the funding from the University of Costa Rica (Grants ED-2033, 115-B0-800, 115-C4-132) and the support from the Laboratorio Nacional de Nanotecnologa, LANOTEC-CeNAT-CONARE
Thus, DSePA, while radio-sensitizing lung cancer cells, prevents radiation-induced chronic inflammatory response in the normal lung parenchyma
