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A 2025 study expanded these findings across additional cell lines Cancer incidence: Long-term animal studies reported reduced spontaneous tumor formation in epitalon-treated groups, partially addressing the theoretical concern that telomerase activation could promote malignancy Human observations: Khavinson reported improved clinical outcomes in elderly cohorts receiving epithalamin (the precursor extract) over multi-year observation periods, including reduced cardiovascular mortality, though these were not rigorously controlled trials Evidence Assessment# Epitalon has the broadest evidence base of any bioregulator, with consistent results across decades of study

Elsevier, Amsterdam, pp 6171 VanBlargan LA, Goo L, Pierson TC (2016) Deconstructing the antiviral neutralizing-antibody response: implications for vaccine development and immunity

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