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Lactate buildup at the site of chronic inflammation promotes disease by inducing CD4+ T cell metabolic rewiring

Molecular mechanisms of AIH Liver metabolism of APAP APAP metabolism mostly occurs in liver microsomes

Bui et al., Figure 1)

Indeed, we found baseline ROS levels close to HC in the transplanted patients PBMCs, hinting at a rescue of the metabolic phenotype upon HSCT in line with the clinical resolution of the patients phenotype (Fig