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A cross-sectional study conducted among elderly Chileans also demonstrated that having a high physiologic folate level (45.3 nmol/L) increased the methylation at the third tertile of specific CpG sites in tumor suppressor gene p16, as well as in the DNA repair genes MLH1 and MGMT [136]
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Vitamin E also exhibits protective effects against other pollutants such as Benzo[a]pyrene (BaP), acrolein, and aluminum nanopowder by preventing oxidative stress [89,90,91]
