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People with deficiencies can experience symptoms that slow them down namely fatigue, lack of mental clarity and a weakened immune system
10.1136/bmjopen-2020-038709 114 ShiotaM.KotaniY.UmemotoM.TobiumeT.HoshiaiH

Barbieri, M., Bonaf, M., Franceschi, C

Functional competence of a partially engaged GPCR--arrestin complex
