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2012;7:e45904
Several reasons have been suggested for the predilection of extraocular muscles (EOM) in MG [18, 19]: (1) EOM twitch fibres have higher firing frequencies, lower density of AChR and less number of packets of ACh released, thereby increasing their susceptibility to fatigue
This specificity theoretically supports a favorable safety profile, though human data remains limited
The ability to survive by relying on glycolysis in hypoxic environments may be an important factor in tumor survival and growth
