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This distinction matters not because B12 injections are inherently dangerous, but because the systems surrounding the injection determine how quickly and effectively a provider can respond if something unexpected occurs

The exposures of interest were concentrations of vitamin B12 biomarkers (plasma vitamin B12, MMA, and holoTC), vitamin B12 intake (from foods and/or supplements), intervention with vitamin B12 (any form, duration, or combination with nutrients or drugs), or genetic variants related to B12 metabolism

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MTHFR and MTRR genotype and haplotype analysis and colorectal cancer susceptibility in a case-control study from the Czech Republic