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Common Acne Types: Comedonal acne : Whiteheads and blackheads Inflammatory acne : Papules, pustules, and nodules Cystic acne : Deep, painful, and prone to scarring Hormonal acne : Often along the jawline, flares around menstrual cycles Conventional Treatment: Why It Often Fails Dermatology often treats acne with: Topicals : Benzoyl peroxide, salicylic acid, retinoids Antibiotics : Doxycycline, minocycline Hormonal agents : Birth control, spironolactone Isotretinoin (Accutane) : For severe cystic acne These can be helpful but often come with downsides: Temporary relief Rebound breakouts Side effects : Gut issues, liver stress, mood swings No investigation of root cause Functional medicine asks a different question: Why is your body producing acne in the first place

Moreover, biomarker-guided treatment and nanomedicine-enabled delivery systems provide a foundation for precision medicine approaches that could enhance both safety and effectiveness

They work from within to reduce melanin production and improve skin tone

3.2.2.2 Genetics related to the inflammatory response Recent studies show that genetic variations in inflammatory genes, particularly TNF- and IL-6, may accelerate DR development