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More importantly, phytochemicals are proposed as one of the most promising mitochondria-targeting medicine to preserve the activity and structure of mitochondria and neurons [174]

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Despite a dearth of comprehensive evidence for numerous pharmacological interventions, healthcare providers have turned to symptomatic treatments to mitigate a spectrum of issues, including psychological distress like anxiety and depression, emotional volatility (pseudobulbar affect), involuntary muscle twitches, pervasive fatigue, sleep disturbances, and a range of physical discomforts from muscle cramps and spasms to immobility-induced musculoskeletal pain, neuropathic pain, sialorrhea, spasticity, constipation, and urinary urgencies

Chen Y, Xu R (2016) Phenome-based gene discovery provides information about Parkinsons disease drug targets