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Sampaio, A

Immunomodulation and Enhanced Immune Surveillance Aging is accompanied by a well-documented decline in immune function known as immunosenescence a state characterized by reduced T-cell proliferation, declining natural killer (NK) cell activity, and impaired antibody responses

Notably, ingredients matter to consumers when it comes to skincare since 43% of consumers consider it an important factor when purchasing skincare products

Furthermore, RA is also thought to be driven by a generation of neoantigens through post-translational modifications of proteins, most commonly by citrullination (also known as deimination)the replacement of the ketamine group in arginine with a ketone group, which effectively removes the positive charge of arginine at neutral pH and converts arginine to the non-coded amino acid citrulline [208, 209]