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Among the 26 genes, two transcription factors (TFs)

Hcy is implicated in cardiovascular disease through diverse mechanisms, including the heightened proliferation of muscle cells leading to vessel constriction, modification of blood coagulation properties, oxidative damage to the vascular endothelium, and harm to arterial walls [49]

As studies used different scales of measurement, SMDs were chosen to summarize between group differences since it can better adjust for the different scaling used [26]

Thomas Brabletz: Writing review & editing, Writing original draft, chapter 2.2.1
